Portrait | Portfolio | Incumbent |
| President Commander-in-chief of the Armed Forces | | Samia Suluhu |
| Vice President | | Philip Mpango |
| President of Zanzibar (Semi-autonomous region) | | Hussein Mwinyi |
| Prime Minister | | Kassim Majaliwa MP |
| Deputy Prime Minister & Minister of Energy | | Doto Biteko MP |
| Ministers of State in the President's Office Regional Administration, Local Government, Civil Service, Good Governance, Planning and Investment | | George Mkuchika MP |
| | George Simbachawene MP |
| | Mohamed Mchengerwa MP |
| | Kitila Mkumbo |
| Minister of State in the Vice President's Office Union Affairs and Environment | | Selemani Jafo MP |
| Minister of State in the Prime Minister's Office Policy, Parliamentary Affairs, Labour, Employment, Youth and the Disabled | | Joyce Ndalichako MP |
| Jenista Mhagama MP |
| Minister of Agriculture | | Hussein Bashe MP |
| Minister of Livestock and Fisheries | | Abdallah Ulega MP |
| Minister of Constitutional Affairs and Justice | | Pindi Chana MP |
| Minister of Defence and National Service | | Stergomena Tax MP |
| Minister of Education, Science, Technology and Vocational Training | | Adolf Mkenda MP |
| Minister of Minerals | | Anthony Mavunde MP |
| Minister of Finance | | Mwigulu Nchemba MP |
| Minister of Foreign Affairs, E.A.C., Regional and International Cooperation | | January Makamba MP |
| Minister of Health, Seniors and Children | | Ummy Mwalimu MP |
| Minister of Community Development & Gender | | Dorothy Gwajima MP |
| Minister of Home Affairs | | Hamad Masauni MP |
| Minister of Industry & Trade | | Ashatu Kijaji MP |
| Minister of Culture, Artists and Sports | | Damas Ndumbaro MP |
| Minister of Lands, Housing and Human Settlements | | Jerry Silaa MP |
| Minister of Natural Resources and Tourism | | Angellah Kairuki MP |
| Minister of Works | | Innocent Bashungwa MP |
| Minister of Transport | | Makame Mbarawa MP |
| Minister of Water and Irrigation | | Jumaa Aweso MP |
| Minister of News, Communication & ICT | | Nape Nnauye MP |
Also attending Cabinet meetings (excluding voting rights) |
| Attorney General | | Eliezer Feleshi |